The briefing

Start the First Dose storyline from Ron’s map marker and complete the chain beginning with Welcome to the Troupe. Finishing the story supplies a Brickade 6×6 and leads to the Acid Lab equipment setup. Mutt then offers the lab installation for GTA$750,000; that is separate from later production equipment.

The equipment upgrade requires ten Fooligan Jobs. Call Dax and choose Request Work to begin them. The cited baseline payment is GTA$50,000 per job, with a 48-minute interval before the next request. Weekly bonuses can alter that payment, so the unlock requirement and the temporary earnings multiplier are different facts.

Keep the lab supplied through Mutt in person or by phone while outdoors. The source compares upgraded and unupgraded supply consumption, production time and net return in the tables. Use the daily production boost when appropriate and account for purchased supplies before estimating profit. Armor for the Brickade is a vehicle-protection purchase, not a substitute for the equipment upgrade.

Maps & reference images

GTA 5 Online: New Acid Lab Business Money Making Guide - Grand Theft Auto V
GTA 5 Online: New Acid Lab Business Money Making Guide - Grand Theft Auto V · Source ↗
acid lab production boost
acid lab production boost · Source ↗
Reference table 1
Without Equipment UpgradeWith Equipment Upgrade
3.2 batches of supplies ($192,000)1.6 batches of supplies ($96,000)
Reference table 2
Without Equipment UpgradeWith Equipment Upgrade
Without 1 Time Daily Boost6 hours4 hours
With 1 Time Daily Boost4.5 hours3 hours
Reference table 3
Without Equipment UpgradeWith Equipment Upgrade
Product Value$237,600$335,200
Supply Cost$192,000$96,000
Net Profit$45,600$239,200

Sources & further reading

Original announcement or supporting source ↗

Original announcement or supporting source ↗

Source reference: GTABase ↗

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